Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.

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Our patient had a confirmed increase in pulmonary arterial pressure that could not be entired explained by the OSA syndrome. This page was last edited on 30 Julyat Author information Article notes Copyright and License information Disclaimer.

Arterial intima and media calcification: Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. This condition does not lead to symptoms or signs of limb or organ ischemia.

Case Report A year-old man with a medical history of stage III nasopharyngeal cancer, end-stage renal disease treated with dialysis, hyperthyroidism, type 2 diabetes mellitus, hypertension, atrial fibrillation, and secondary hyperparathyroidism presented at the Oral Medicine Clinic of the College of Dentistry, University of Florida for dental evaluation prior to the start of radiotherapy.

Mönckeberg’s sclerosis – is the artery the only target of calcification?

The vascular phenotype in Pseudoxanthoma elasticum and related disorders: To the best of our knowledge, soft tissue calcifications have never been described in such disease, especially in association with obstructive sleep apnea OSA. Vascular smooth muscle cells in the pathogenesis of vascular calcification. We conclude that, in cases of patients with peripheral obstructive arterial disease with undefined etiology and absence of traditional risk factors, it should be remembered that calcification of Monckeberg’s medial layer, despite being rare, can be the cause of peripheral vasculopathy.

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Continuing navigation will be considered as acceptance of this use. Best Pract Res Clin Rheumatol, 24pp. Published online Mar The resected mass was sent for histopathologic examination. Monckeberg’s sclerosis stands among the differential diagnoses of vasculitis, however, its clinical relevance has been undervalued due to the low clinical impact attributed to it and the low reported incidence, being considered as a condition secondary to a process of deposit of inert calcium.

Received May 21; Accepted Sep This drug has the property to attach to hydroxyapatite crystals preventing both vascular and soft tissue calcification[ 16 ]. The corrected calcium was 9. The authors declare they do not have any conflict of interest. A transesophageal echocardiogram was carried out, which reported segmental contractility disorders and valve leaflets without the presence of vegetations, but with multiple atheromatous plaques in the entire aortic trajectory.

Diabetes Care, 17pp. Pathogenesis and clinical significance of Monckeberg medial calcinosis.

There are situations in which it is possible to perform anastomoses, avoiding artery clamping. Author information Article notes Copyright and License information Disclaimer.

However, it can occur in pseudoxanthoma elasticum and idiopathic arterial calcification of moncieberg as a pathological condition, as well. Report of case and litera Monckeberg’s sclerosis can be an unexpected contraindication to arterial puncture in patients planned for coronary angiography and percutaneous intervention.

National Center for Biotechnology InformationU. The left lower limb was painless, hyperemic, with normal femoral pulse and absence of popliteal and distal pulses.

We also thank the patient for giving us a written consent for publishing his case.

Prevalence of peripheral arterial disease – results of the Heinz Nixdorf recall study. Arteritis Aortitis Buerger’s disease.

On physical examination, he had cold and edematous right lower limb, with absence of popliteal and distal pulses, marked pallor at limb elevation, moderate reactive hyperemia and venous filling time of 45 seconds.

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Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Monckeberg’s sclerosis and atherosclerosis. Lanzer 9 reported a case of Monckeberg’s arteriosclerosis involving the aorta, pelvic and lower limb arteries. Clinically, the calcified vessel is described as a “pipe-stem” artery, which is visible on plain radiographs as “rail-tracking” of the vessel.

Am J Physiol Endocrinol Metab. Media calcification and intima calcification are distinct entities in chronic kidney disease. We report the case of a year-old diabetic man, who was incidentally detected to have extensive calcification in arteriosclerossi upper limb arteries, consistent with Monckeberg’s sclerosis.

Monckeberg’s arteriosclerosis as a cause of lower limb critical ischemia: case report

Clinical and laboratory findings excluded any kind of rheumatologic disease such as dermatomyositis, scleroderma or systemic lupus erythematosus.

Direct laryngoscopic examination shows exophytic calcic deposits in the left pyriform sinus arrow. Its diagnosis is difficult, and requires histopathological studies. Vascular calcification is a common consequence of aging and is more frequent in patients with diabetes, dyslipidemia, genetic diseases, and diseases involving disturbances of calcium metabolism.

Radiographic manifestations of Mönckeberg arteriosclerosis in the head and neck region

Open in a separate window. Arch Pathol Lab Med. Vascular calcification results from monckebergg deposition of calcium phosphate crystals hydroxyapatite as a consequence of disordered calcium phosphate regulation in the blood vessel. The following examinations showed slight changes: Alternatively, treatment with intravenous dissodic pamidronate was attempted to stop the phenomenon of calcification and prevent further airway obstruction.

Medial calcinosis does not obstruct the lumina of the arteries, and therefore does not lead to symptoms or signs of limb or organ ischemia.

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